Table 1

mtDNA mutations found in infertile patients

Type of Infertility

Gene

At nucleotide position

At amino acid position

Nature of mutation


Asthenozoospermia

ND2

T4823C

V118V

Silent

Asthenozoospermia

ND2

T4993C

L175F

Novel

Asthenoteratozoospermia

ND2

C4730T

T87T

Silent

Asthenoteratozoospermia

ND2

T5250G

L261V

Novel

Asthenoteratozoospermia

ATPase8

G8557C

L64F

Novel

Oligoasthenoteratozoospermia

ATPase6

T8614G

L30V

Novel

Oligoasthenoteratozoospermia

ATPase6

A8925G

T133T

Silent

Oligoasthenoteratozoospermia

ATPase6

G9064A

A180T

Novel

Oligoasthenoteratozoospermia

ND4

A10978G

L73L

Silent


Barbhuiya et al. BMC Proceedings 2012 6(Suppl 6):P31   doi:10.1186/1753-6561-6-S6-P31

Open Data