Pharmacokinetic comparison of pdFIX, CHOrFIX, HEK293rFIX, and high-phospho/sulfo HEK293rFIX in FIX-knock-out mice. Plasma concentrations of FIX after administration are shown as mean values ± standard deviations with n = 10 mice for each timepoint. Dose adjustment was done by normalizing to start material concentrations.

Böhm et al. BMC Proceedings 2011 5(Suppl 8):P23   doi:10.1186/1753-6561-5-S8-P23