This article is part of the supplement: International Conference on Prevention & Infection Control (ICPIC 2011)

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Epidemiologic profile of Staphylococcus aureus-methicilin resistant (MRSA) bacterium in hospital-acquired-infection in neonatal-intensive-care-unit (ICU) from -2000 to 2010 analysis in general hospital

LF Baqueiro-Freitas1,2*, CI Santos2 and F Ferreira3

  • * Corresponding author: LF Baqueiro-Freitas

Author Affiliations

1 Internal Medicine, University of Sao Paulo, Ribeirao Preto, Brazil

2 Infection Control Service, Santa Lydia Hospital, Ribeirão Preto, Brazil

3 Microbiology, Santa Lydia Hospital, Ribeirão Preto, Brazil

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BMC Proceedings 2011, 5(Suppl 6):P173 doi:10.1186/1753-6561-5-S6-P173


The electronic version of this article is the complete one and can be found online at: http://www.biomedcentral.com/1753-6561/5/S6/P173


Published:29 June 2011

© 2011 Baqueiro-Freitas et al; licensee BioMed Central Ltd.

Introduction / objectives

Awareness of epidemiologic profile of MRSA-hospital-acquired infection in neonatal-ICU might improve an early recognition of this infection.

Evaluating the clinical epidemiologic profile of hospital-acquired Staphylococcus aureus-bacterium infection in neonatal-ICU patients according to its methicilin sensibility.

Methods

The infections cases were prospectively recorded for an eleven-year period from 2000 to 2010; the program used was EPI-INFO v 3.4.1.

Results

31 strains of Staphylococcus sp were identified in some hospital-acquired-infections. 46.7% of Staphylococcus aureus were methicilin resistant. Bloodstream infection (BSI) was the most prevalent site of infection of MRSA (40%) as well as for methicilin-sensitive Staphylococcus aureus (MSSA) (62.5%). Symptoms of infection had began as early as 8.5 days and as late as 11 days (average time) from the admission date in methicilin-sensitive and methicilin-resistant Staphylococcus aureus cases respectively. The previous antibiotic therapy was more usual in MRSA cases (80%) than in MSSA (0%). The average weight of newborn infant was heavier in MSSA (2.222g) than MRSA (1626g). The frequency of death was higher in MRSA than MSSA (40% and 12,5% respectivelly). The average duration of stay was slightly longer in MRSA (24 days) than in MSSA (22.8 days).

Conclusion

From that analysis we have pointed out an epidemiologic profile of MRSA-hospital infections in neonatal-ICU concerning its prevalence and others epidemiologic issues in order to prevent its increase and diffusion in neonatal ICU.

Disclosure of interest

None declared.