This article is part of the supplement: Proceedings of the International Symposium on Animal Genomics for Animal Health (AGAH 2010)
Using SNP array data to test for host genetic and breed effects on Porcine Reproductive and Respiratory Syndrome Viremia
- Equal contributors
1 Parco Tecnologico Padano-Loc. Cascina Codazza, Via A. Einstein, 26900 Lodi Italy
2 The Roslin Institute and R(D)SVS, University of Edinburgh, Roslin, Midlothian EH25 9PS Scotland, UK
3 Instituto di Biologia e Biotecnologia Agraria - CNR, Loc. Cascina Codazza, Via A. Einstein, 26900 Lodi, Italy
4 Current address: INRA, UMR 1313 de Génétique Animale et Biologie Intégrative, Jouy-en-Josas, France – and - AgroP arisTech, UMR 1313 de Génétique Animale et Biologie Intégrative, Jouy-en-Josas, France
BMC Proceedings 2011, 5(Suppl 4):S28 doi:10.1186/1753-6561-5-S4-S28Published: 3 June 2011
The effect of breed on Porcine Reproductive and Respiratory Syndrome Viremia (PRRSV) was tested using data collected in 17 Italian commercial pig farms and 1096 genotypes obtained by the PorcineSNP60 BeadChip. A binomial logistic model was used to investigate the relationship between breed-clusters and PRRSV susceptibility. Breed-clusters were defined using the matrix of genomic kinship between all pairs of piglets.
Only the contemporary group effect, defined as all piglets reared in the same herd, in the same year and whose samples were collected in the same season, was significant. Sex, age and breed-cluster showed no statistically significant effect on PRRS viremia, although the Landrace and Cross breed-clusters showed the lowest Odds-Ratio
The model failed to detect a significant breed-cluster effect, highlighting the impact of environment and management on PRRS viremia incidence. Incomplete exposure over the observed period may have masked possible breed differences.