Four genomic regions. (A) Null region 1 - low LD; (B) Null region 2 - high LD; (C) Associated region - PTPN22 (D) Associated region - PADI4. SNPs in boxes indicate those removed for imputation of completely untyped markers. For associated regions (A and B), boxes indicate SNPs which were imputed: blue boxes denote the set containing the imputed risk SNP (first SNP set) and green boxes denote the set including flanking markers to the risk SNP (second SNP set).
Fridley et al. BMC Proceedings 2009 3(Suppl 7):S7