Predicted measurement distribution over time (standard particle filter) during simulation run. Patients from control group. Development of predicted measurement distributions over time during simulation run with parameters estimated by the standard particle filter. Circles: Measurements. Solid line: Median of simulated measurements. Violet shaded area: Measurement distributions based on empirical quantiles.
Krengel et al. BMC Systems Biology 2013 7:8 doi:10.1186/1752-0509-7-8