Additional file 4.

Figure S2. Cell response distribution during decreasing-concentration trajectories. Cell response distribution for decreasing-concentration trajectories for lux01 (left) and lux02 (right) strains in the stochastic model. Cells are initially induced at <a onClick="popup('http://www.biomedcentral.com/1752-0509/7/6/mathml/M45','MathML',630,470);return false;" target="_blank" href="http://www.biomedcentral.com/1752-0509/7/6/mathml/M45">View MathML</a> for 2 hours. The concentration of exogenous autoinducer <a onClick="popup('http://www.biomedcentral.com/1752-0509/7/6/mathml/M46','MathML',630,470);return false;" target="_blank" href="http://www.biomedcentral.com/1752-0509/7/6/mathml/M46">View MathML</a> is then hourly decreased in order to simulate the experiments (see [10]). The cell distribution reveals the variety of cell trajectories in comparison to the deterministic population average solution (green line). The cells jump to the high state for a wide range of times and autoinducer concentrations. Note also that fluctuations leads to a stabilization of the low state with respect to the deterministic solution.

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Weber and Buceta BMC Systems Biology 2013 7:6   doi:10.1186/1752-0509-7-6