Figure 3.

A view of CCIs with the subcellar localizations of the annotated complexes. Each node represents a complex and edges represent interactions. Node size represents the number of proteins in a complex and the thickness of edges connecting complexes, which are exponential to the number of PPIs between connected nodes. Node colors indicate subcellular localization of the annotated complexes; dark red: nucleus, blue: cytoplasm, green: membrane, purple: nucleus and cytoplasm, yellow: Golgi apparatus, blue-green: cytoplasm and membrane, light blue: cytoplasm, membrane and nucleus, orange: mitochondria, light red: endoplasmic reticulum, light green: endosome, gray: other subcellular localization, black: NA/unknown.

Kikugawa et al. BMC Systems Biology 2012 6(Suppl 2):S7   doi:10.1186/1752-0509-6-S2-S7