Figure 4.

Model of genetic regulation with a positive autoregulatory feedback loop and time delays. Case I: time delay τ1 in the degradation process of TF-A; Case II: time delay τ2 = τ' + τ″, with τ' the time taken for the transcription of tf-a mRNA and its movement to translation and τ″ the time required for movement of TF-A protein to the nucleus.

Wang et al. BMC Systems Biology 2012 6(Suppl 1):S9   doi:10.1186/1752-0509-6-S1-S9