Figure 2.

Bifurcation plot for the steady state of TF-A on the control parameter of transcription rate k_f. The system in the region (i.e., 5.45 < k_f <6.68) exhibits bistability. The other parameters are fixed as dissociation constant of TF-A dimer from TF-REs K_d = 10, the degradation constant k_d = 1, and the basal rate of TF-A synthesis R_bas = 0.4.