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This article is part of the supplement: Selected articles from The 5th IEEE International Conference on Systems Biology (ISB 2011)

Open Access Research

The preservation of bidirectional promoter architecture in eukaryotes: what is the driving force?

Chao Xu, Jiajia Chen and Bairong Shen*

Author Affiliations

Center for Systems Biology, Soochow University, Suzhou 215006, China

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BMC Systems Biology 2012, 6(Suppl 1):S21  doi:10.1186/1752-0509-6-S1-S21

Published: 16 July 2012

Additional files

Additional file 1:

Predicted peaks of distribution of distance between TSSs of head to head gene pairs using two mixed Gaussian distribution. The approximate positions of the minor and major peaks in the distance distributions were fitted in all the eight organisms. The average value for the minor peak and major peak were computed afterwards.

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Additional file 2:

Distribution of distance between genes and adjacent genes on opposite strand in human when including the non-coding transcripts. a). The distribution when only considering protein-coding genes. b). The distribution when including non-coding genes. The non-coding transcripts were defined as the genes labelled by 'lincRNA', 'miRNA', 'miscRNA', 'rRNA', 'snoRNA', 'snRNA', 'non-coding', 'processed_transcript' in biotype term in Ensembl Build 58.

Format: PDF Size: 107KB Download file

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Open Data