Evaluation of the functional, splicing, transcriptional, and protein complex homogeneity of co-splicing clusters with different recurrences. Four types of databases are used: (A) Gene Ontology for functional enrichment, (B) SpliceAid2 database for splicing enrichment, (C) ENCODE database for transcriptional and epigenetic enrichment, and (D) CORUM database for protein complex enrichment. The x-axis is network recurrence and y-axis is enrichment fold ratio, calculated by dividing the percentage of enriched clusters by the percentage of enriched random clusters.
Dai et al. BMC Systems Biology 2012 6(Suppl 1):S17 doi:10.1186/1752-0509-6-S1-S17