Table 1

Comparison with multiple E. coli gene essentiality studies

Protein

Gene

Criticality

Flux-sum

Keio collection

Genetic footprinting

PEC database


PGK

pgk

Critical

GAPDH

gapA

Critical

ENO

eno

Critical

ALDO

fbaA

Critical

PGI

pgi

Uncritical

PK

pykF

Uncritical

PGM

pgm

Uncritical

Ru5P

rpe

Critical

G1PAT

glgC

Uncritical


Our characterizations of protein criticality (Col 3) are compared with multiple gene essentiality studies (Col 5-7) besides the validations through flux-sum (Col 4).

Note: "√" means this evidence supports the characterization of criticality

Li and Liu BMC Systems Biology 2012 6(Suppl 1):S11   doi:10.1186/1752-0509-6-S1-S11

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