Screen-shot of a real-time simulation. Users can change the activity level of the extracellular species via simple sliders (boxed in red). Each tracing in the graph corresponds to an activity level of a species specified in the legend by the user. Any effects of the change of activity of the external species is then reflected in the dynamics of the species’ graph; as the user moves the slider, the activity patterns of the selected species change in real time. In addition, by using the “Mutate” button, users can simulate the effects of gain/loss-of-function mutations on the dynamics the modeled biological process.
Helikar et al. BMC Systems Biology 2012 6:96 doi:10.1186/1752-0509-6-96