Integration of laboratory results via modeling. The different relationships between hypothetical interactions of X and Y with Z as discovered by scientists A and B. Solid lines depict the necessity of the interaction for species Z to be activated, whereas dashed lines correspond the optional nature of the interaction. Because scientist B’s results suggest an “OR” relationship between the regulators, there are two graphical representations of Z’s regulatory mechanism.
Helikar et al. BMC Systems Biology 2012 6:96 doi:10.1186/1752-0509-6-96