Figure 4.

Parametric analysis for the reduced switch model. Application of parametric reduced models for parametric analysis: Illustration of the clean and noisy signals y(t,θref) and ymeas(t), respectively (left), the optimization target J(θ) over the parameter domain (middle), interactive parameter exploration by a graphical user interface (right).

Waldherr and Haasdonk BMC Systems Biology 2012 6:81   doi:10.1186/1752-0509-6-81
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