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Open Access Research article

A regulatory network modeled from wild-type gene expression data guides functional predictions in Caenorhabditis elegans development

Brandilyn Stigler1* and Helen M Chamberlin2

Author Affiliations

1 Department of Mathematics, Southern Methodist University, Dallas, TX 75275, USA

2 Department of Molecular Genetics, Ohio State University, Columbus, OH, 43210, USA

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BMC Systems Biology 2012, 6:77  doi:10.1186/1752-0509-6-77

Published: 26 June 2012

Additional files

Additional file 1:

Table S1. Supporting Excel workbook for modeling and analysis. All presented models, computations, and results are supported by the Excel workbook in Additional file 2; note that many of the spreadsheets in the workbook contain formulas that reference multiple spreadsheets. See the tab “README” for a listing and description of the contents.

Format: XLS Size: 918KB Download file

This file can be viewed with: Microsoft Excel Viewer

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Additional file 2:

Graphs and performance plots for the MIM built using COV-MSA. Figure S1. contains the graphs comprising the MIM using the COV-MSA pipeline. S2 contains the Precision-Recall and ROC plots for this model.

Format: PDF Size: 335KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data