Model 2 - Histograms of multistart local searches. Objective function values achieved by local searches starting from different points with the FMINSEARCH (Figure8.a), DHC (Figure8.b), and N2FB (Figure8.c) methods. Calculations were carried out in a single processor; the computation time was 240 hours for each method. The best values obtained were: 3.046·103(FMINSEARCH), 7.601·102(DHC), and 1.3863·103(N2FB). Note that the x axis is logarithmic in order to represent the large dispersion of the results.
Villaverde et al. BMC Systems Biology 2012 6:75 doi:10.1186/1752-0509-6-75