Model 1 - Histograms of multistart local searches. Objective function values achieved by local searches starting from different points with the FMINSEARCH (Figure3.a), DHC (Figure3.b), and FMINCON (Figure3.c) methods. Calculations were carried out in a single processor and the computation time was 10 days for each method. The best values obtained were: 5.367·105(FMINSEARCH), 2.938·101(DHC), and 1.459·103(FMINCON).
Villaverde et al. BMC Systems Biology 2012 6:75 doi:10.1186/1752-0509-6-75