Table 3

Transition probabilities for single mutations C1-C4

G+

G-

P+T+

P-T-

P+T-

P-T+


C1


G+

0.251

0

0.008

0

0

0

G-

0

0.329

0

0

0.003

0

P+T+

0.015

0

0.180

0.013

0

0

P-T-

0

0

0.015

0.157

0

0

P+T-

0

0.0049

0

0

0.031

0

P-T+

0

0

0

0

0

0


C2


G+

0

0

0.007

0

0

0

G-

0

0.82

0

0

0.007

0

P+T+

0.008

0

0.022

0.001

0

0

P-T-

0

0

0.043

0.039

0

0

P+T-

0

0.007

0

0

0.039

0

P-T+

0

0

0

0

0

0


C3


G+

0.317

0

0.008

0

0

0

G-

0

0.242

0

0

0.026

0

P+T+

0.023

0

0.030

0

0

0

P-T-

0

0

0

0

0

0

P+T-

0

0.043

0

0

0.174

0.046

P-T+

0

0

0

0

0.046

0.151


C4


G+

0.815

0

0.019

0

0

0

G-

0

0

0

0

0.019

0

P+T+

0

0

0.037

0

0

0

P-T-

0

0

0

0

0

0

P+T-

0

0.037

0

0

0.037

0

P-T+

0

0

0

0

0

0.037


Table 3,4,5 and 6 list the transition probabilities between functions for every motif and its respective function probability distribution. The values are obtained from numerical simulation.

Widder et al. BMC Systems Biology 2012 6:7   doi:10.1186/1752-0509-6-7

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