Table 4

Top 10 up-regulated glycoproteins in SaOS-2/LM7 model

Gene

Symbol

Accession #

LM7/

SaOS-2

p-value Unique Peptides Function
VIM IPI00418471 350

1 x

10E-42

22 Filaments expressed in neoplasms originated from mesenchymal cells
TPM1 IPI00940084 130 2.2 x 10E-41 2 Contractile system of muscles and the cytoskeleton of non-muscle cells
ALB IPI00022434 120

2 x

10E-38

9 Primarily a carrier protein in serum
ODZ3 IPI00398020 97 1.1 x 10E-30 2 May function as signal transducer
KRT5 IPI00009867 90 1.4 x 10E-28 2 Filaments found in basal layer of epidermis
WDR49 IPI00216853 86 2.7 x 10E-27 2 Regulates cell division, cell-fate determination, gene transcription, and transmembrane signaling
A2M IPI00478003 84 1.9 x 10E-26 6 Inhibits all classes of proteinases by a unique 'trapping' mechanism
NES IPI00010800 81 1.3 x 10E-25 16 Disassembly of vimentin, role in the trafficking and distribution of cellular factors during progenitor cell division
CAL2 IPI00916600 70 3.4 x 10E-22 3 Mediates the control of numerous enzymes and proteins by calcium
ANXA5 IPI00329801 58 2.4 x 10E-18 6 Anticoagulant, inhibitor of the thromboplastin-specific complex

Flores et al.

Flores et al. BMC Systems Biology 2012 6:50   doi:10.1186/1752-0509-6-50

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