Table 1

Top 10 up-regulated genes in HOS/143B model
Up-regulated genes Entrez Gene HOS/143B (Log2) p-value Function
FOXR1 283150 8 8.4 x 10E-6 Play roles in determining cell fates during early development
RTN1 6252 7 1.1 x 10E-5 Involved in membrane trafficking in neuroendocrine cells
FRMD3 257019 7 1.7 x 10E-5 Structural protein essential for erythrocyte shape and mechanical properties
HOXA9 3205 7 1.4 x 10E-5 Transcription factor which may regulate gene expression, morphogenesis and differentiation
ANGPT2 285 7 9.4 x 10E-6 In concert with VEGF, may serve as a permissive angiogenic signal
KRT18 3875 6 1.1 x 10E-5 Involved in the uptake of thrombin-antithrombin complexes by hepatic cells
IL10RA 3587 6 1.0 x 10E-5 Interferon receptor that mediates the immunosuppressive signal of IL10
TPD52 7163 6 2.0 x 10E-5 Uncharacterized function, but expressed in many tumor cell lines including colon, breast, prostate, pancreas and kidney
CA2 760 6 1.8 x 10E-5 Essential for bone resorption and osteoclast differentiation
BEND4 389206 6 1.2 x 10E-5 Uncharacterized function, but known to be phosphorylated upon DNA damage

Flores et al.

Flores et al. BMC Systems Biology 2012 6:50   doi:10.1186/1752-0509-6-50

Open Data