Open Access Highly Accessed Research article

Spice: discovery of phenotype-determining component interplays

Zhengzhang Chen12, Kanchana Padmanabhan12, Andrea M Rocha3, Yekaterina Shpanskaya4, James R Mihelcic3, Kathleen Scott5 and Nagiza F Samatova12*

Author Affiliations

1 Department of Computer Science, North Carolina State University, Raleigh, NC 27695, USA

2 Computer Science and Mathematics Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA

3 Department of Civil and Environmental Engineering, University of South Florida, Tampa, FL 33620, USA

4 Trinity College of Arts and Sciences, Duke University, Durham, NC 27708, USA

5 Department of Integrative Biology, University of South Florida, Tampa, FL 33620, USA

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BMC Systems Biology 2012, 6:40  doi:10.1186/1752-0509-6-40

Published: 14 May 2012

Additional files

Additional file 1:

17H 2-producing and 11 H2-non-producing microorganisms.

Format: XLS Size: 320KB Download file

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Additional file 2:

Enzymes associated with biohydrogen production detected by SPICE.

Format: XLSX Size: 17KB Download file

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Additional file 3:

COG data with 17 microorganisms for biohydrogen production.

Format: XLSX Size: 269KB Download file

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Additional file 4:

COG modules related to biohydrogen production detected by SPICE.

Format: XLSX Size: 18KB Download file

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Additional file 5:

COG data with 141 microorganisms for motility phenotype.

Format: XLSX Size: 2.1MB Download file

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Additional file 6:

COG modules related to motility detected by SPICE.

Format: XLSX Size: 44KB Download file

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Additional file 7:

Cancer-related gene modules detected on Leukemia data.

Format: ZIP Size: 13KB Download file

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Additional file 8:

Pseudo-code of SPICE algorithm.

Format: ZIP Size: 18KB Download file

Open Data