Phenotype of genes encoding components of protein complexes as a function of copy number is context dependent. A. Cytosolic ribosomal proteins have positive slope in turbidostats B-C. The range of significant FCC's for cytosolic ribosomal proteins. D. Sign of slope of the phenotype-copy number curve for genes specifying proteasome subunits. E-F. Range of significant FCC's for proteasomal proteins.
Pir et al. BMC Systems Biology 2012 6:4 doi:10.1186/1752-0509-6-4