Additional file 3.

Figure S1Projection pipeline from S. cerevisiae scaffold model to Y. lipolytica iNL895. The three main parts of our pipeline for the reconstruction of the Y. lipolytica model are: Projection, where the S. cerevisiae scaffold model and the information from different sources of orthology between S. cerevisiae and Y. lipolytica are used to produce a draft model, Curation, where the expert curators revised the candidates for gap-filling and added species-specific reactions and Validation, where experiments obtained from the literature were compared with our simulations, producing a detailed accuracy report.

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Loira et al. BMC Systems Biology 2012 6:35   doi:10.1186/1752-0509-6-35