Simplified network model of acetate production in E. coli. A. Simplified metabolic network. Reaction 1: glycolysis, reaction 2: acetate excretion, reaction 3: lactate/ethanol excretion, reaction 4: TCA-cycle, reaction 5: Oxidative phosphorylation; B. Growth yield distribution of the full simplified network; C. Growth yield distribution in simplified model with blocked acetate excretion.
van Hoek and Merks BMC Systems Biology 2012 6:22 doi:10.1186/1752-0509-6-22