Table 3

PPI and network property z-score of crosstalk motifs with zero and non-zero functional similarity

TF

TF-miRNA

miRNA


z-score

PPI

Network

PPI

Network

PPI

Network


0

5.71

12.96

6.15

11.81

5.68

9.63


> 0

8.89

16.43

8.68

14.59

8.03

12.38


p-value

2.07E-15

1.89E-11

8.29E-29

2.31E-13

3.87E-42

2.02E-24


*P-values were derived from Wilcoxon rank-sum test. TF and miRNA represented TF-TF and miRNA-miRNA combinations respectively. Network represented the average z-score of the network properties. Z-scores in this table were averaged.

Lin et al. BMC Systems Biology 2012 6:18   doi:10.1186/1752-0509-6-18

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