Table 5

Top 13 reactions over-represented in tumor tissue models versus corresponding normal tissue models
Reactionsa % tumor models % normal models Rank sum p-value
ALOX5 72% 6% 8.6E-05
ALOX52 72% 6% 8.6E-05
EX_leuktrC4(e) 72% 6% 8.6E-05
GGT5r 72% 6% 8.6E-05
GGT6 72% 6% 8.6E-05
GLUtr 72% 6% 8.6E-05
GTHRDtr 72% 6% 8.6E-05
LEUKTRA4tr 72% 6% 8.6E-05
LEUKTRC4t 72% 6% 8.6E-05
LEUKTRD4tr 72% 6% 8.6E-05
LTC4CP 72% 6% 8.6E-05
LTC4Sr 72% 6% 8.6E-05
LTD4DP 72% 6% 8.6E-05

aThese reactions form a pathway that catalyzes the production of leukotrienes from arachidonic acid.

Wang et al.

Wang et al. BMC Systems Biology 2012 6:153   doi:10.1186/1752-0509-6-153

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