Open Access Research article

Modeling and analysis of flux distributions in the two branches of the phosphotransferase system in Pseudomonas putida

Andreas Kremling1*, Katharina Pflüger-Grau1, Max Chavarría2, Jacek Puchalka35, Vitor Martins dos Santos4 and Víctor de Lorenzo2

Author Affiliations

1 Fachgebiet Systembiotechnologie, Technische Universität München, Garching b. München, Germany

2 Systems Biology Program, Centro Nacional de Biotecnología-CSIC, Campus Cantoblanco, Madrid, Spain

3 , Helmholtz Center for Infection Research, Braunschweig, Germany

4 , Wageningen University & Research centre, Agrotechnology & Food Sciences, Wageningen, Netherlands

5 , Present address: University Children’s Hospital

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BMC Systems Biology 2012, 6:149  doi:10.1186/1752-0509-6-149

Published: 6 December 2012

Additional files

Additional file 1:

The files describes the model equations and the kinetic parameters.

Format: PDF Size: 137KB Download file

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Additional file 2:

The xls-sheet gives all values for the flux distributions based on a FBA analysis for different growth conditions. The xls-sheet is subdivided into two parts.In the first part, the values for the growth conditions are summarized; afterwards the flux for each reaction for the different conditions is provided. For all conditions, three columns are shown: given are the nominal value, and minimal/maximal values based on FVA. Reactions with PEP and pyruvate as substrate (S) or product (P) are highlighted.

Format: XLS Size: 248KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data