Figure 8.

Simulation of influence of glutathione on production of 5-LO metabolites (sum of LTA4, HP and HT). Parameters of the LOS model used for simulation: pool of NADP 3 mM; NADPH 2 mM; Ca 1 mM; 5-LO 0.1 μM; HEDH5 0.1 μM; Values of parameter PL responsible for steady state AA level are 117 (solid), 120 (dash), 125 (dot).

Karelina et al. BMC Systems Biology 2012 6:141   doi:10.1186/1752-0509-6-141
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