Quantitative simulation of experimentwith different inhibitors. Consumption of 10 μM HP by 5-LO system in presence of 10 μM PF (dotted line) or 10 μM Zileuton (solid line) or in the absence of inhibitors (dashed line, coinciding with dotted line). Concentrations: PL 40 μM, pool of glutathione 10 mM, GSH 5 mM. Other parameters are as in the legend to Figure 8.
Karelina et al. BMC Systems Biology 2012 6:141 doi:10.1186/1752-0509-6-141