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Open Access Research article

Gene autoregulation via intronic microRNAs and its functions

Carla Bosia12*, Matteo Osella34*, Mariama El Baroudi5, Davide Corà26 and Michele Caselle27

Author Affiliations

1 Human Genetics Foudation (HuGeF), V. Nizza 52, Torino, I-10126, Italy

2 Center for Complex Systems in Molecular Biology and Medicine, University of Torino, V. Accademia Albertina 13, I-10100 Torino, Italy

3 Genomic Physics Group, UMR 7238 CNRS “Microorganism Genomics”, Paris, 75006, France

4 Université Pierre et Marie Curie, Paris, 75006, 15 rue de L’École de Médecine, France

5 National Research Council (CNR), Institute of Informatics and Telematics (IIT) and Institute of Clinical Physiology (IFC), Laboratory for Integrative System Medicine (LISM), Via Giuseppe Moruzzi 1, Pisa, I-56124, Italy

6 IRC@C: Institute for Cancer Research at Candiolo, School of Medicine, University of Torino, Str. Prov. 142, Km. 3.95, Torino, Candiolo I-10060, Italy

7 Dipartimento di Fisica Teorica and INFN, University of Torino, V. Pietro Giuria 1Torino, I-10125, Italy

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BMC Systems Biology 2012, 6:131  doi:10.1186/1752-0509-6-131

Published: 10 October 2012

Additional files

Additional file 1:

Supplementary information. Single pdf file containing the details of our modeling strategy, a comparison with alternative models of microRNA regulation, and the results of our bioinformatic analysis.

Format: PDF Size: 756KB Download file

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