Table 6

Outlining how the concentration of cholesterol in the liver was determined (Non obese subjects (n=19))
Liver sample Liver homogenate Liver microsomes Total
Mean free cholesterol 42.4 nmol/mg 24.7 nmol/mg 67.1 nmol/mg
Mean esterified cholesterol 9.9 nmol/mg 8.6 nmol/mg 18.5 nmol/mg
Total Hepatic Cholesterol 115.6 nmol/mg
Molecular weight of cholesterol 386.66 Used to convert nmol to milligrams
Total cholesterol 44.6979 μg/mg or 0.0446979 mg/mg
Total esters 7.1539 μg/mg or 0.0071532 mg/mg
Total free cholesterol 37.5447 μg/mg or 0.0375447 mg/mg
Size of Human Liver = 1.5 kg [89] 1.5kg=1500000 mg
0.0446979 *1500000=67046.85 mg total cholesterol
0.0071532 * 1500000=10792.80 mg of cholesterol esters
0.0375447*1500000=56317.5 mg of free cholesterol

Mc Auley et al.

Mc Auley et al. BMC Systems Biology 2012 6:130   doi:10.1186/1752-0509-6-130

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