(A-E) Changes to cholesterol absorption in the range 30-85%.A-D) simulations of the model using MathSBML to show the response of LDL-C to changes in the rate of efficiency of cholesterol absorption in the range 30-80% over a number of different time periods. E) Steady-state levels of LDL-C for various different percentages of cholesterol absorption. This was generated with the software tool Copasi.
Mc Auley et al. BMC Systems Biology 2012 6:130 doi:10.1186/1752-0509-6-130