The probability that the target site is occupied by a TF molecule. The proportion of time the O1 target site was occupied by lacI molecules during the simulation time was measured using 60 independent simulations. Only lacI molecules were added to the system and each simulation was run for: 2000 s (in the case of 10 molecules), 200 s (in the case of 100 molecules) and 20 s (in the case of 1000 molecules). On the first row none of the parameters are changed, while on the second and third ones the number of lacI molecules and the association rate was varied according to the system size.
Zabet BMC Systems Biology 2012 6:121 doi:10.1186/1752-0509-6-121