Additional file 13.

Gene expression annotation. The identification of human heart tissue specific reactions requires a tissue specific gene expression profile. We obtained gene expression samples from different gene expression data available from Gene Expression Omnibus, including GDS181 and GSE1145. This table provides gene expression information annotated to metabolic reactions of the cardiomyocyte network. Each reaction identifier refers to a compartment localisation of the respective metabolic reaction. Furthermore, each entry in the table provides information about annotated Ensemble Gene ID, Geo Dataset ID, Geo Sample ID, Probeset ID, Gene ID, gene expression value and detection call. The information of gene expression status can be obtained from the column “Detection call”. Each expression is either categorized as present (P), absent (A) or M (marginal). We further considered genes as expressed for gene expression values with a cut-off greater than 100.

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Karlstädt et al. BMC Systems Biology 2012 6:114   doi:10.1186/1752-0509-6-114