Simulations and lab results experiment #26. A: Reprint of figure 6D and E from  (License agreement number 2838800627526): Quantitative reverse transcription-PCR analysis of MITF target genes (c-Kit and TPH) and STAT3 target genes (c-Myc and VEGF) from BMMC activated for 0.5 or 4h with SCF derived from either wild-type or MITFdi/di mice. (B and C) Simulations of the same experiment (experiment #26 in Table 2). Note that the di/di mutation blocks the activation of both MITF and STAT3 in the reprinted lab result while in the simulation STAT3 activity is not affected.
Thingnes et al. BMC Systems Biology 2012 6:11 doi:10.1186/1752-0509-6-11