Table 4 |
||||||
| Comparison of iBMA-prior, iBMA-shortlist and Lirnet in network construction on the Brem data | ||||||
| Method | Network size | p-value of chi square testa | TPR (%)b | # misclass.c | TP | O/Ed |
| iBMA-prior | 8000 | 7.75E-65 | 15.62 | 10198 | 323 | 2.41 |
| iBMA-shortlist | 35995 | 1.02E-59 | 10.99 | 14581 | 818 | 1.70 |
| Lirnet | 10491 | 1.90E-03 | 8.42 | 10080 | 132 | 1.30 |
a The p-value of Pearson’s chi-square test measures the strength of association between an inferred network and the Yeastract database.
b True positive rate (TPR) is defined as the proportion of inferred regulatory relationships that are documented in Yeastract.
c The number of misclassified cases is the sum of false positives and false negatives.
d The O/E ratio is the number of folds the observed number of recovered relationships (i.e., TP) in excess of the expected count of recovery by chance.
Lo et al. BMC Systems Biology 2012 6:101 doi:10.1186/1752-0509-6-101
