Table 4

Comparison of iBMA-prior, iBMA-shortlist and Lirnet in network construction on the Brem data
Method Network size p-value of chi square testa TPR (%)b # misclass.c TP O/Ed
iBMA-prior 8000 7.75E-65 15.62 10198 323 2.41
iBMA-shortlist 35995 1.02E-59 10.99 14581 818 1.70
Lirnet 10491 1.90E-03 8.42 10080 132 1.30

a The p-value of Pearson’s chi-square test measures the strength of association between an inferred network and the Yeastract database.

b True positive rate (TPR) is defined as the proportion of inferred regulatory relationships that are documented in Yeastract.

c The number of misclassified cases is the sum of false positives and false negatives.

d The O/E ratio is the number of folds the observed number of recovered relationships (i.e., TP) in excess of the expected count of recovery by chance.

Lo et al.

Lo et al. BMC Systems Biology 2012 6:101   doi:10.1186/1752-0509-6-101

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