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This article is part of the supplement: The 2010 International Conference on Bioinformatics and Computational Biology (BIOCOMP 2010): Systems Biology

Open Access Research article

An integrated proteomics analysis of bone tissues in response to mechanical stimulation

Jiliang Li1, Fan Zhang23 and Jake Y Chen234*

Author Affiliations

1 Department of Biology, Purdue School of Science, Indiana University Purdue University Indianapolis (IUPUI), Indianapolis, IN 46202, USA

2 Indiana University School of Informatics, Indianapolis, IN 46202, USA

3 Indiana Center for Systems Biology and Personalized Medicine, Indianapolis, IN 46202, USA

4 Department of Computer and Information Science, Purdue University School of Science, Indianapolis, IN 46202, USA

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BMC Systems Biology 2011, 5(Suppl 3):S7  doi:10.1186/1752-0509-5-S3-S7

Published: 23 December 2011

Additional files

Additional file 1:

Protein quantification data for the 21 Rat genes whose proteins levels are significantly changed in Loaded (L) or Fully Loaded (FL) conditions compared with controls (CON). "CON_L" refers to comparing L to CON. "CON_FL" refer to comparing FL to CON. "FL_L" refers to comparing L to FL. q-value refers to adjusted p-values. While p-value is an estimate of false positive rate, q-value is an estimate of false discovery rate (FDR). FC refers to Fold Change. "Mean CON/L/FL" refers to mean protein intensities. "%CV Injection" refers to % Coefficient of Variation for injection variation, "%CV Inj + Sample %" refers to the Coefficient of Variation for injection plus sample variation. "# of peptides/group" refers to the number of distinct identified peptides for this protein in any of the three groups: CON, L, or FL. "Mean Xcorr" refers to the mean Xcorr of the peptides identified for this protein.

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