Comparison of degree distribution of major depressive disorder (MDD), schizophrenia (SCZ), and cancer genes. The disease genes were grouped by their degree into degree bins. Here, degree was measure by the number of interactors for each disease gene in the human interactome. The top panel shows the histogram degree distribution, and the bottom panel shows the curve degree distribution. In the bottom panel, each vertical line represents the median value of the degrees in each disease category. Note that MDD and SCZ candidate genes had the same median value of degrees so that their vertical lines could not be distinguished.
Jia et al. BMC Systems Biology 2011 5(Suppl 3):S12 doi:10.1186/1752-0509-5-S3-S12