Table 2

Estimated size and power (each condition has three replicates).

Lambda1

Lambda1

LRT

Cond

Wald

Wald-Log

VST

Fisher


5

5

0.0012

0.0009

0.0009

0.0027

0.0012

0.0009

7

0.0102

0.0062

0.0077

0.0175

0.0103

0.0062

9

0.0786

0.0542

0.0652

0.1150

0.0786

0.0542

11

0.2517

0.2008

0.2265

0.3160

0.2517

0.2008

13

0.5204

0.4581

0.4940

0.5872

0.5204

0.4581


10

10

0.0008

0.0002

0.0006

0.0016

0.0008

0.0002

12

0.0045

0.0029

0.0042

0.0065

0.0045

0.0029

14

0.0316

0.0229

0.0279

0.0389

0.0316

0.0229

16

0.1100

0.0882

0.1019

0.1272

0.1100

0.0882

18

0.2602

0.2198

0.2454

0.2883

0.2603

0.2198

20

0.4670

0.4210

0.4515

0.5005

0.4672

0.4210


15

15

0.0007

0.0003

0.0007

0.0007

0.0007

0.0003

17

0.0034

0.0026

0.0031

0.0049

0.0034

0.0026

19

0.0181

0.0144

0.0172

0.0221

0.0182

0.0144

21

0.0612

0.0505

0.0583

0.0712

0.0618

0.0505

23

0.1442

0.1251

0.1395

0.1648

0.1460

0.1251

25

0.2850

0.2564

0.2759

0.3125

0.2869

0.2564


30

30

0.0014

0.0010

0.0013

0.0016

0.0014

0.0010

34

0.0074

0.0057

0.0071

0.0082

0.0074

0.0057

38

0.0520

0.0457

0.0505

0.0570

0.0520

0.0457

42

0.2073

0.1846

0.2034

0.2210

0.2073

0.1846

46

0.4543

0.4270

0.4486

0.4701

0.4543

0.4270


Estimated size and power from each method for detecting the difference of means between two Poisson distributions. There are three replicates for each condition. The Poisson means for the first condition are 5, 10, 15, or 30. The second Poisson means are the same as (for size) or larger than (for power) the first ones. The nominal size (significance level) is 10-3 and 10,000 runs are used for each setting.

Chen et al. BMC Systems Biology 2011 5(Suppl 3):S1   doi:10.1186/1752-0509-5-S3-S1

Open Data