Table 1

Estimated size and power (no replicates for each condition).

Lambda1

Lambda2

LRT

Cond

Wald

Wald-Log

VST

Fisher


5

5

0.0128

0.0002

0.0002

0.0185

0.0011

0.0002

9

0.0199

0.0066

0.0074

0.0522

0.0176

0.0066

13

0.0842

0.0492

0.0550

0.1737

0.0916

0.0492

17

0.2484

0.1877

0.1964

0.3976

0.2626

0.1877

21

0.4903

0.4248

0.4358

0.6269

0.4981

0.4248

25

0.7146

0.6547

0.6685

0.8077

0.7168

0.6547


10

10

0.0013

0.0004

0.0005

0.0041

0.0013

0.0004

15

0.0114

0.0082

0.0089

0.0256

0.0124

0.0082

20

0.0729

0.0504

0.0571

0.1190

0.0737

0.0504

25

0.2433

0.1863

0.2110

0.3217

0.2435

0.1863

30

0.4848

0.4111

0.4460

0.5746

0.4848

0.4111

35

0.7177

0.6625

0.6900

0.7859

0.7177

0.6625

40

0.8750

0.8414

0.8599

0.9102

0.8750

0.8414


15

15

0.0012

0.0007

0.0009

0.0030

0.0012

0.0007

20

0.0075

0.0047

0.0052

0.0140

0.0075

0.0047

25

0.0456

0.0314

0.0377

0.0689

0.0456

0.0314

30

0.1483

0.1130

0.1305

0.1990

0.1483

0.1130

35

0.3422

0.2868

0.3167

0.4121

0.3422

0.2868

40

0.5692

0.5046

0.5459

0.6266

0.5692

0.5046

45

0.7563

0.7047

0.7393

0.8002

0.7563

0.7047

50

0.8907

0.8569

0.8796

0.9096

0.8907

0.8569


30

30

0.0011

0.0007

0.0011

0.0019

0.0011

0.0007

40

0.0180

0.0125

0.0163

0.0224

0.0180

0.0125

50

0.1464

0.1167

0.1370

0.1704

0.1464

0.1167

60

0.4776

0.4292

0.4620

0.5109

0.4777

0.4292

70

0.7840

0.7526

0.7750

0.8145

0.7848

0.7526

80

0.9421

0.9299

0.9390

0.9514

0.9423

0.9299


Estimated size and power from each method for detecting the difference of two Poisson means. There are no replicates for each condition. The Poisson means for the first condition are 5, 10, 15, or 30. The second Poisson means are the same as (for size) or larger than (for power) the first ones. The nominal size (significance level) is 10-3 and 10,000 runs are used for each setting.

Chen et al. BMC Systems Biology 2011 5(Suppl 3):S1   doi:10.1186/1752-0509-5-S3-S1

Open Data