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This article is part of the supplement: 22nd International Conference on Genome Informatics: Systems Biology

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Novel Markov model of induced pluripotency predicts gene expression changes in reprogramming

Zhirui Hu2, Minping Qian3 and Michael Q Zhang12*

Author Affiliations

1 Department of Molecular and Cell Biology, Center for Systems Biology, the University of Texas at Dallas, 800 West Campbell Road, RL11 Richardson, TX 75080-3021, USA

2 MOE Key Laboratory of Bioinformatics and Bioinformatics Div, TNLIST /Department of Automation, Tsinghua University, Beijing 100084, China

3 School of Mathematics, Peking University, Beijing 100871, China

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BMC Systems Biology 2011, 5(Suppl 2):S8  doi:10.1186/1752-0509-5-S2-S8

Published: 14 December 2011

Additional files

Additional file 1:

Details and application of the model Including 11 figures and 1 table; Simulating MET in reprogramming; Mathematics details

Format: DOCX Size: 461KB Download file

Open Data

Additional file 2:

Gene expression data This file includes normalized gene expression data in different days in reprogramming.

Format: XLSX Size: 8.3MB Download file

Open Data