Combined networks in the immune functional category in GK rat. The appearance of each sub-network at time points is distinguished by the same way as Figure 1. Many proinflammatory related pathways active comparing GK to WKY rats. There are two hubs CYBB and ATF2 that play important role in immune damages observed in GK.
Zhou et al. BMC Systems Biology 2011 5(Suppl 1):S16 doi:10.1186/1752-0509-5-S1-S16