Table 2 |
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|
Enriched gene ontology level 3 categories of biological processes. |
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|
gene ontology term |
set size |
candidates contained |
p-value |
q-value |
|
|
|
|||||
|
GO:0006986 |
response to unfolded protein |
73 |
8 |
3.11E-009 |
7.03E-007 |
|
GO:0070841 |
inclusion body assembly |
13 |
4 |
4.26E-007 |
4.82E-005 |
|
GO:0006091 |
generation of precursor metabolites and energy |
363 |
11 |
2.02E-006 |
1.52E-004 |
|
GO:0032507 |
maintenance of protein location in cell |
80 |
6 |
3.14E-006 |
1.77E-004 |
|
GO:0016052 |
carbohydrate catabolic process |
132 |
7 |
4.67E-006 |
1.93E-004 |
|
GO:0051651 |
maintenance of location in cell |
87 |
6 |
5.13E-006 |
1.93E-004 |
|
GO:0012501 |
programmed cell death |
1338 |
20 |
7.18E-006 |
2.32E-004 |
|
GO:0010941 |
regulation of cell death |
1136 |
18 |
1.06E-005 |
2.99E-004 |
|
GO:0046907 |
intracellular transport |
855 |
15 |
2.08E-005 |
5.21E-004 |
|
GO:0002349 |
histamine production involved in inflammatory response |
2 |
2 |
2.56E-005 |
5.25E-004 |
|
GO:0043455 |
regulation of secondary metabolic process |
2 |
2 |
2.56E-005 |
5.25E-004 |
|
GO:0002443 |
leukocyte mediated immunity |
184 |
7 |
4.05E-005 |
7.64E-004 |
|
GO:0044248 |
cellular catabolic process |
1028 |
16 |
4.56E-005 |
7.92E-004 |
|
GO:0050777 |
negative regulation of immune response |
40 |
4 |
4.91E-005 |
7.93E-004 |
|
GO:0070727 |
cellular macromolecule localization |
610 |
12 |
5.29E-005 |
7.98E-004 |
|
GO:0051235 |
maintenance of location |
133 |
6 |
5.79E-005 |
8.18E-004 |
|
|
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|
Set size refers to the number of entities that have a Uniprot ID as stated in the corresponding GO category at the ConsensusPathDB site. The number of candidates contained refers to amount of proteins identified in this study that appear as part of the GO category. P-values are calculated according to a hypergeometric test; q-values represent p-values corrected for multiple testing using the false discovery rate method. |
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|
Higareda-Almaraz et al. BMC Systems Biology 2011 5:96 doi:10.1186/1752-0509-5-96 |
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