Table 2

Enriched gene ontology level 3 categories of biological processes.

gene ontology term

set size

candidates contained

p-value

q-value


GO:0006986

response to unfolded protein

73

8

3.11E-009

7.03E-007

GO:0070841

inclusion body assembly

13

4

4.26E-007

4.82E-005

GO:0006091

generation of precursor metabolites and energy

363

11

2.02E-006

1.52E-004

GO:0032507

maintenance of protein location in cell

80

6

3.14E-006

1.77E-004

GO:0016052

carbohydrate catabolic process

132

7

4.67E-006

1.93E-004

GO:0051651

maintenance of location in cell

87

6

5.13E-006

1.93E-004

GO:0012501

programmed cell death

1338

20

7.18E-006

2.32E-004

GO:0010941

regulation of cell death

1136

18

1.06E-005

2.99E-004

GO:0046907

intracellular transport

855

15

2.08E-005

5.21E-004

GO:0002349

histamine production involved in inflammatory response

2

2

2.56E-005

5.25E-004

GO:0043455

regulation of secondary metabolic process

2

2

2.56E-005

5.25E-004

GO:0002443

leukocyte mediated immunity

184

7

4.05E-005

7.64E-004

GO:0044248

cellular catabolic process

1028

16

4.56E-005

7.92E-004

GO:0050777

negative regulation of immune response

40

4

4.91E-005

7.93E-004

GO:0070727

cellular macromolecule localization

610

12

5.29E-005

7.98E-004

GO:0051235

maintenance of location

133

6

5.79E-005

8.18E-004


Set size refers to the number of entities that have a Uniprot ID as stated in the corresponding GO category at the ConsensusPathDB site. The number of candidates contained refers to amount of proteins identified in this study that appear as part of the GO category. P-values are calculated according to a hypergeometric test; q-values represent p-values corrected for multiple testing using the false discovery rate method.

Higareda-Almaraz et al. BMC Systems Biology 2011 5:96   doi:10.1186/1752-0509-5-96

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