Simplified pathway and drug interactions. Shown are simplified pathways targeted in the three and four-drug combination treatment of nonsmall cell lung cancer cells A549 and primary fibroblast AG02603 cells that are already known or reported. The dashed arrows indicate indirect connections.
Al-Shyoukh et al. BMC Systems Biology 2011 5:88 doi:10.1186/1752-0509-5-88