Table 3 |
|||
|
Fibroblast ECM array in serum free control and 10 ng/ml TGF-β stimulated fibroblasts |
|||
|
Serum Free |
TGF-β |
p Value |
|
|
|
|||
|
ECM/Growth Factors |
|||
|
|
|||
|
Col1a1 |
4.842 ± 1.399 |
9.614 ± 3.324 |
0.028 |
|
|
|||
|
Col5a1 |
0.301 ± 0.085 |
0.605 ± 0.230 |
0.038 |
|
|
|||
|
Fbln1 |
0.012 ± 0.005 |
0.008 ± 0.004 |
0.032 |
|
|
|||
|
Sparc |
2.709 ± 0.204 |
4.932 ± 0.379 |
<0.001 |
|
|
|||
|
Tgfbi |
0.022 ± 0.016 |
0.013 ± 0.015 |
0.009 |
|
|
|||
|
Cell Adhesion Molecules |
|||
|
|
|||
|
Ncam1 |
0.043 ± 0.016 |
0.169 ± 0.054 |
0.011 |
|
|
|||
|
Pecam1 |
0.000060 ± 0.000012 |
0.000022 ± 0.000011 |
0.015 |
|
|
|||
|
Sgce |
0.187 ± 0.035 |
0.146 ± 0.018 |
0.030 |
|
|
|||
|
Vcam1 |
0.301 ± 0.136 |
0.161 ± 0.088 |
0.031 |
|
|
|||
|
MMPs/TIMPs |
|||
|
|
|||
|
Mmp7 |
0.0000075 ± 0.0000011 |
0.0000056 ± 0.0000004 |
0.026 |
|
|
|||
|
Timp1 |
0.052 ± 0.022 |
0.272 ± 0.136 |
0.035 |
|
|
|||
|
Timp2 |
0.326 ± 0.109 |
0.188 ± 0.050 |
0.027 |
|
|
|||
|
Data are Avg ± SEM levels (2-ΔCT) normalized to 5 housekeeping genes for n = 4 paired fibroblast sets. |
|||
|
Jin et al. BMC Systems Biology 2011 5:60 doi:10.1186/1752-0509-5-60 |
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