Table 3

Fibroblast ECM array in serum free control and 10 ng/ml TGF-β stimulated fibroblasts

Serum Free

TGF-β

p Value


ECM/Growth Factors


Col1a1

4.842 ± 1.399

9.614 ± 3.324

0.028


Col5a1

0.301 ± 0.085

0.605 ± 0.230

0.038


Fbln1

0.012 ± 0.005

0.008 ± 0.004

0.032


Sparc

2.709 ± 0.204

4.932 ± 0.379

<0.001


Tgfbi

0.022 ± 0.016

0.013 ± 0.015

0.009


Cell Adhesion Molecules


Ncam1

0.043 ± 0.016

0.169 ± 0.054

0.011


Pecam1

0.000060 ± 0.000012

0.000022 ± 0.000011

0.015


Sgce

0.187 ± 0.035

0.146 ± 0.018

0.030


Vcam1

0.301 ± 0.136

0.161 ± 0.088

0.031


MMPs/TIMPs


Mmp7

0.0000075 ± 0.0000011

0.0000056 ± 0.0000004

0.026


Timp1

0.052 ± 0.022

0.272 ± 0.136

0.035


Timp2

0.326 ± 0.109

0.188 ± 0.050

0.027


Data are Avg ± SEM levels (2-ΔCT) normalized to 5 housekeeping genes for n = 4 paired fibroblast sets.

Jin et al. BMC Systems Biology 2011 5:60   doi:10.1186/1752-0509-5-60

Open Data