A working model of post-MI scar formation and remodeling with constructive and destructive modules. Red arrows represent the destruction pathway and green arrows represent the construction pathway. The regulation scheme includes lines in black, which can be a driving or a triggering stimulus. LV remodeling outcomes are denoted as collagen concentrations in the scar tissue.
Jin et al. BMC Systems Biology 2011 5:60 doi:10.1186/1752-0509-5-60