Receptor occupation when affinity surfaces partially overlapped within a cluster. A) Comparison of occupation as a function of relative overlap of affinity surfaces. On a single curve, points correspond to the same experiment, for a fixed ligand concentration, but with varying overlap. Error bars are ± standard deviation. B) Cartoon representing increasingly overlapped receptor affinity surfaces within clusters.
Caré and Soula BMC Systems Biology 2011 5:48 doi:10.1186/1752-0509-5-48