Additional file 1.

Supplemental Material. This file contains Table S1 (Yeast strains), a description of the mathematical models, Figure S1 (Parametric analysis of k0 and k1), Table S2 (Effect of gradient slope versus noise on polarization), Table S3 (Effects of noise on polarization quality), a section estimating external gradient noise, Table S4 (Effects of ligand diffusion noise (σL) and receptor-ligand binding noise (σRL) on projection directional accuracy), a comparison of chemotactic index to cos(θ) measure of directional accuracy, Table S5 (Effect of diffusion of the polarized species on polarization), Figure S2 (Diffusion decreases noise in polarization output and the extent of polarization), and Figure S3 (Image of microfluidics gradient labeled with tracer dye).

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Chou et al. BMC Systems Biology 2011 5:196   doi:10.1186/1752-0509-5-196